Search on: PULMONARY SURFACTANT ASSOCIATED PROTEIN A 
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Descriptor English:   Pulmonary Surfactant-Associated Protein A 
Descriptor Spanish:   Proteína A Asociada a Surfactante Pulmonar 
Descriptor Portuguese:   Proteína A Associada a Surfactante Pulmonar 
Synonyms English:   SP-A Protein
Surfactant Protein A
Pulmonary Surfactant Associated Protein A
SP A Protein  
Tree Number:   D12.776.503.280.249.600
D12.776.823.100
Definition English:   An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins. 
Indexing Annotation English:   see SCR for species-specific terms; DF: SP-A PROTEIN
Pharmacological Action:   Pulmonary Surfactants
 
History Note English:   2003; for SURFACTANT PROTEIN A & SP-A PROTEIN use PULMONARY SURFACTANT-ASSOCIATED PROTEINS (NM) 1991-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   37462 
Unique Identifier:   D037662 

Occurrence in VHL:
 

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